MASTERPOST: Autism & ADHD in EDS/HSD

This is an ongoing compilation of studies related to autism & ADHD in hypermobility and hereditary diseases of connective tissue (such as EDS, Marfan’s, and Osteogenesis Imperfecta). Some other neurodiverse conditions such as developmental coordination disorder are included as well.

Autism

Lowerlimb Joint Laxity in Children with Autism Spectrum Disorders. (2019)

A Cohort Study Comparing Women with Autism Spectrum Disorder with and without Generalized Joint Hypermobility (2018) (PDF Link)

Autism and heritable bone fragility: A true association? (2018) (Ostogenesis Imperfecta + ASD)

Autism, Joint Hypermobility-Related Disorders and Pain (2018)

Autism Spectrum Disorders and Ehlers-Danlos Syndrome Hypermobility-Type: Similarities in clinical presentation (2016) (PDF Link)

Abnormalities of joint mobility and gait in children with autism spectrum disorders (2012) (PDF Link)

High-functioning autistic disorderwith Ehlers-Danlos syndrome (2011, Case Study)

Autism and Ehlers-Danlos Syndrome (1992, Letter to the Editor) (PDF Link)

Asperger’s Syndrome and Ligamentous Laxity (1990, Case Study) (PDF Link)

ADHD

Attention-deficit/hyperactivity disorder, joint hypermobility-related disorders and pain: expanding body-mind connections to the developmental age (2018) (PDF Link)

Connective tissue problems and attention deficit and hyperactivity (2015) (PDF Link)

Pilot Study of Attention Deficit Hyperactivity Disorder-related Behaviors in a Pediatric Ehlers-Danlos Syndrome-Hypermobility type Population (2015)

Evaluation of the Prevalence of Joint Laxity in Children with Attention Deficit/Hyperactivity Disorder (2013)

Benign Joint Hypermobility Syndrome in Patients with Attention Deficit/Hyperactivity Disorders (2011)

DCD:

Phenotypic variability in developmental coordination disorder: Clustering of generalized joint hypermobility with attention deficit/hyperactivity disorder, atypical swallowing and narrative difficulties (2015) (PDF Link)

Association between Joint Hypermobility Syndrome and Developmental Coordination Disorder – A Review (2012)

Developmental Coordination Disorder and Joint Hypermobility Syndrome – overlapping disorders? Implications for research and clinical practice (2006) (PDF Link)

General/Multiple Neurodevelopmental Conditions:

Generalised joint hypermobility and neurodevelopmental traits in a non-clinical adult population (2018) (PDF Link)

A connective tissue disorder may underlie ESSENCE problems in childhood (2017) (PDF Link)

Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers–Danlos syndrome or hypermobility syndrome and their siblings (2016)

Joint hypermobility and the heritable disorders of connective tissue: clinical and empirical evidence of links with psychiatry (2015) (PDF Link)

Neurodevelopmental attributes of joint hypermobility syndrome/Ehlers–Danlos syndrome, hypermobility type: Update and perspectives (2015) (PDF Link)

Psychopathological manifestations of joint hypermobility and joint hypermobility syndrome/ Ehlers–Danlos syndrome, hypermobility type: The link between connective tissue and psychological distress revised (2015) (PDF Link)

Joint Hypermobility and Autonomic Hyperactivity: Relevance to Neurodevelopmental Disorders (2014, Abstract) (PDF Link)

Joint hypermobility and the heritable disorders of connective tissue: clinical and empirical evidence of links with psychiatry (2014) (PDF Link)

A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk (2013) (Marfan’s + ASD)

Brain structure and joint hypermobility: relevance to the expression of psychiatric symptoms (2012) (PDF Link)

Concomitant neuropsychiatric symptoms in a case of Ehlers-Danlos syndrome (1985, Case Study)